1. The Left Hand
In the beginning, it will be necessary to work on each hand individually to get a feel for the separate functions of each hand. Begin by working the left hand first. Pick any fret on the first string and place your first finger there. Repeatedly press down and release on that fret for approximately one minute. Then repeat this process using the other three fingers. Remember to only focus on your left hand. Do not attempt to pick any notes with your right hand at this point.
2. The Right Hand
After you have spent some time working with the left hand, you'll want to get a feel for the right hand as it picks the string. Take away your left hand and focus on picking the open first string. Notice how it feels as the pick hits the string and try to find a consistent volume and speed for each pick stroke.
3. Both Hands Together
The next step is to try both hands together. Start by getting your left hand going again, and focus on just one finger at a time. Repeatedly lift and place your finger on whatever fret you choose. Once you feel comfortable, add the right hand and try to pick the string at precisely the same moment you press down the note with your left hand. This precise timing in both hands is the key element of two-hand synchronization.
Once you develop a feel for this practice strategy, you can try applying it to more difficult exercises. For example, you can try moving to different frets or changing strings after every note.